Page personnelle

Thomas GICQUEL, MCU-PH


Skills

Liquid chromatography coupled to Mass spectrometry (LC-HR-MS/MS)
small interfering RNA electroporation

Research topics and scientific objectives

Ethanol and drugs
Drugs Metabolism
Purinergic and Inflammasome pathway

Education and main positions held

Associate professor (MCU-PH) in Pharmacology & Biologist in Biological and Forensic Toxicology laboratory – Faculty of Pharmacy and University Hospital, Rennes, France

Ph D in Biology – University of Rennes 1, Rennes, France

Pharmaceutical Doctor (Pharm D)

Current projects

Ethanol as a NLRP3 inflammasome inhibitor and its metabolism

Molecular Networking in human biological samples

Forensic Toxicology

Selected publications

IL-1β production is dependent of the activation of purinergic receptors and NLRP3 pathway in human macrophages.
Gicquel T., Robert S., Loyer P., Victoni T., Bodin A., Ribault C., Gleonnec F., Couillin I., Boichot E., Lagente V.
FASEB J


Ethanol upregulates the P2X7 purinergic receptor in human macrophages
Le Daré B., Victoni T., Bodin A., Vlach M., Vene E., Loyer P., Lagente V., Gicquel T.
Fundam Clin Pharmacol




Death associated with consumption of Rauwolfia sp.
Gicquel T., Hugbart C., Le Devehat F., Lepage S., Baert A., Bouvet R., Morel I.
Forensic Sci Int


HAL Publications

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