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Isabelle LURON, DR


Skills

• Nutritional programming
• Nutrition
• Gut physiology
• Microbiota-host crosstalk

Research topics and scientific objectives

• Understand the impact of early nutrition (maternal diet and infant formula composition) on gut physiology and consequences in adults facing an adverse nutritional environment
• Decipher the importance of early bacterial colonization on intestinal homeostasis later in life and relationship with glucose metabolism

Education and main positions held

Current projects

CLIMAPIG : Research collaborative project with the industry – Impact of infant formula composition on gut digestion and physiology and glucose metabolism using the mini-pig as model for human infant and adult.
FOSGUT : Research collaborative project with the industry – Impact of fructooligosaccahrides on intestinal physiology and glucose metabolism using the pig as model for human infant and adult.
EPIPIG : Research collaborative project with the industry – Importance of early bacterial colonization on further sensitivity to digestive disorders
HED-O-SHIFT : Identification of intestinal phenotypes correlated with neuro-behavioral patterns in obese mini-pigs undergoing laparoscopic Roux-en-Y gastric bypass

Selected publications

Infant formula interface and fat source impact on neonatal digestion and gut microbiota.
Bourlieu C, Bouzerzour K, Ferret-Bernard S, Le Bourgot C, Chever S, Ménard O, Deglaire A, Cuinet I, Le Ruyet P, Bonhomme C, Dupont D and Le Huërou-Luron I
European Journal of Lipid Sciences and Technology 117, in press


Maternal short-chain fructooligosaccharide supplementation influences intestinal immune system maturation in piglets.
Le Bourgot C, Ferret-Bernard S, Le Normand L, Savary G, Menendez-Aparicio E, Blat S, Appert-Bossard E, Respondek F, Le Huërou-Luron I
Plos One, 9:e107508


Dietary protein excess during neonatal life alters colonic microbiota and mucosal response to inflammatory mediators later in life in female pigs.
Boudry G, Jamin A, Chatelais L, Gras-Le Guen C, Michel C, Le Huërou-Luron I
Journal of Nutrition, 143: 1225-1232


Maternal 18:3n-3 favors piglet intestinal passage of LPS and promotes intestinal anti-inflammatory response to this bacterial ligand.
Desaldeleer C, Ferret-Bernard S, de Quelen F, Le Normand L, Perrier C, Savary G, Romé V, Michel C, Mourot J, Le Huërou-Luron I, Boudry G
Journal of Nutritional Biochemistry, 25 : 1090-1098.



HAL Publications

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